CD8 Antikörper (APC)

Produktnummer ABIN118127

Der Ratte Monoklonal Anti-CD8 Antikörper wurde für FACS validiert. Er ist geeignet, CD8 in Proben von Maus zu detektieren.

Kurzübersicht für CD8 Antikörper (APC) (ABIN118127)

Target: CD8

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD8 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: KT15

Produktdetails anti-CD8 Antikörper (APC)

Spezifität: Mouse Ly2.1 and Ly2.2 cells. This antibody reacts with the CD8 alpha chain (non polymorphic).

Immunogen: T cell clone, C6. Spleen cells from a Spraque Dawley rat immunised with the C6 T cell clone were fused with cells of the NSO mouse myeloma cell line.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cellsexpressing low affinity Fc recepto
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water

Buffer: PBS containing 0.09 % Sodium Azide, 5 % Sucrose and 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: Use of Sodium Azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

Handhabung: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD8

Target: CD8

Andere Bezeichnung: CD8

Hintergrund: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Gen-ID: 12525

NCBI Accession: NP_001074579

UniProt: P01731